Fibrinogen Level

Also Know as: Coagulation Factor I Test

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Last Updated 1 December 2024

What is Fibrinogen Level

Fibrinogen level refers to the amount of fibrinogen, a type of protein produced by the liver, present in your blood. This protein plays a crucial role in blood clotting, healing, and inflammation. Let's dive a little deeper into this topic:

  • Importance: Fibrinogen is pivotal in the body's natural blood clotting process. When there is a wound or injury, fibrinogen converts into fibrin, essential for the formation of a blood clot to prevent excessive bleeding.
  • Fibrinogen Test: A fibrinogen test is done to determine the quantity of fibrinogen in the blood. This test is usually performed if a person has symptoms of a bleeding disorder or abnormal clotting.
  • Normal Levels: Normal fibrinogen levels typically range from 200 to 400 milligrams per deciliter of blood. However, these values can vary depending on the laboratory that analyzes the test.
  • High Fibrinogen Levels: High levels of fibrinogen may indicate a higher risk of heart disease and stroke as it can cause excessive clotting. Conditions like pregnancy, inflammatory diseases, cancer, or heart disease can elevate fibrinogen levels.
  • Low Fibrinogen Levels: Conversely, low fibrinogen levels may cause excessive bleeding since the body cannot form clots effectively. Conditions like liver disease, malnutrition, or genetic disorders can lower fibrinogen levels.

In conclusion, maintaining a balanced fibrinogen level is crucial for the body's clotting mechanism and overall health. Regular check-ups and a healthy lifestyle can help manage these levels effectively.


When is Fibrinogen Level required?

  • A Fibrinogen level test is required when a person shows signs and symptoms of a bleeding disorder. These symptoms may include excessive bleeding from minor injuries, unexplained bruising or blood in the urine and stool. The test helps determine if the patient's blood clots normally.
  • Another instance when fibrinogen level is required is when a person is suffering from conditions that cause inappropriate blood clotting, such as deep vein thrombosis (DVT) or pulmonary embolism (PE). The fibrinogen level test can help evaluate the risk of excessive clotting.
  • Doctors may also order a fibrinogen level test for patients with liver disease. The liver plays a crucial role in producing fibrinogen, so those with liver disease may have lower levels of fibrinogen. This test helps monitor the liver's functionality and the severity of the disease.
  • Lastly, fibrinogen levels may be tested during pregnancy. High levels of fibrinogen during pregnancy can increase the risk of developing blood clots, leading to complications such as preeclampsia, miscarriage, and preterm birth.

Who requires Fibrinogen Level?

  • People who have a family history of bleeding disorders may require a fibrinogen level test to determine if they are at risk. This is because some bleeding disorders are hereditary, so family members may share the same risk.
  • Patients with liver disease require fibrinogen level testing. This is because the liver is responsible for producing fibrinogen, so a lower fibrinogen level could indicate liver dysfunction.
  • Pregnant women, especially those with a history of pregnancy complications, may also require a fibrinogen level test. This is because high fibrinogen levels can increase the risk of blood clot formation, leading to complications during pregnancy.
  • People who have experienced unexplained or prolonged bleeding may need a fibrinogen level test to determine the cause of the bleeding. This can help doctors to diagnose and treat the underlying condition.

What is measured in Fibrinogen Level?

  • Fibrinogen level test measures the amount of fibrinogen in the blood. Fibrinogen is a protein produced by the liver and is essential for blood clotting. Normal fibrinogen levels are typically between 200 and 400 mg/dL.
  • The test can also measure the functionality of fibrinogen. If there's enough fibrinogen in the blood but it's not functioning properly, this can lead to bleeding or clotting problems.
  • In addition to the quantity and quality of fibrinogen, the test can also assess the speed at which fibrinogen is converted into fibrin, a protein that helps in the formation of blood clots. Slow or fast conversion could indicate a potential health problem.
  • A fibrinogen level test is also used to monitor the effectiveness of treatment for disorders that affect fibrinogen levels or functionality. It helps doctors to adjust the treatment plan when necessary.

What is the Methodology of Fibrinogen Level?

  • Fibrinogen level is a blood test that measures the concentration of fibrinogen in your blood. Fibrinogen is a protein produced by the liver and is essential in the formation of blood clots.
  • The fibrinogen level test is primarily used to detect disorders related to fibrinogen. These may include conditions that cause abnormal bleeding and clotting, congenital fibrinogen deficiencies, and acquired fibrinogen abnormalities.
  • The test is also used to monitor therapy for fibrinogen-related conditions. For instance, if you're being treated for disseminated intravascular coagulation or hemophilia, your doctor may use the fibrinogen level test to monitor your response to treatment.
  • The test is usually conducted in a laboratory. A healthcare provider will collect a sample of your blood and send it to the lab for analysis. The blood is typically drawn from a vein in your arm.

How to Prepare for Fibrinogen Level?

  • No special preparation is typically required for a fibrinogen level test. However, it's always important to inform your doctor about any medications or supplements you're currently taking, as some drugs may affect fibrinogen levels.
  • Certain factors can affect fibrinogen levels, including pregnancy, recent surgery, or an infection. Therefore, it's essential to inform your healthcare provider if you have any of these conditions.
  • It's also recommended that you wear a short-sleeved shirt to the appointment or wear clothing with sleeves that can easily be rolled up to facilitate the blood draw.

What Happens During Fibrinogen Level?

  • During the fibrinogen level test, a healthcare provider will clean the area of your arm where the blood will be drawn with antiseptic, and then tie an elastic band around your upper arm to apply pressure and make the vein swell with blood.
  • A needle is then inserted into the vein to draw blood. You may feel a slight sting or prick when the needle is inserted, but the discomfort should be minimal.
  • Once the blood has been collected, the needle is removed, and a small bandage or cotton ball is applied to the puncture site to stop any bleeding.
  • The blood sample is then sent to a laboratory where it will be analyzed for fibrinogen concentration. The results are typically available within a few days.

What is Fibrinogen Level normal range?

Fibrinogen, also known as factor I, is a protein in your blood that helps in clotting. When you get a cut, fibrinogen changes into fibrin and these are the "strands" that form a blood clot.

  • The normal range of fibrinogen in your blood is from 200 to 400 milligrams per deciliter (mg/dL).
  • However, normal value ranges may vary slightly among different labs, and lab results should always be interpreted in relation to the normal value range provided by the lab that performed the test.
  • A higher than normal level may be due to many different conditions, while a lower than normal level can also be indicative of certain health issues.

What are reasons for abnormal Fibrinogen Level normal range?

Abnormal fibrinogen levels can be indicative of a variety of medical conditions and should be addressed by a healthcare professional. The following are some potential reasons for abnormal fibrinogen levels:

  • Increased fibrinogen levels can be seen in conditions like pregnancy, inflammatory disorders, infections, heart disease, and cancers.
  • Decreased fibrinogen levels can be seen in conditions such as liver disease, disseminated intravascular coagulation (DIC), or hereditary fibrinogen deficiencies.

How to maintain normal Fibrinogen Level range?

Maintaining a healthy lifestyle is key in ensuring your fibrinogen levels remain in the normal range. Here are some tips:

  • Maintain a healthy weight. Obesity can increase your fibrinogen levels.
  • Exercise regularly. Physical activity can help keep your fibrinogen levels in check.
  • Eat a balanced diet. Foods high in omega-3 fatty acids, such as fish, can help reduce fibrinogen levels.
  • Quit smoking, if you are a smoker. Smoking can increase your fibrinogen levels.
  • Limit alcohol intake. Regular, heavy alcohol use can increase fibrinogen.
  • Manage stress. High levels of stress can increase your fibrinogen levels.

Precautions and Aftercare tips post Fibrinogen Level test?

After your fibrinogen level test, there are several precautions and aftercare tips that you should follow:

  • After the blood draw, apply pressure to the site to stop any bleeding. If you notice continued bleeding, contact your healthcare provider.
  • If your fibrinogen levels are abnormal, follow your healthcare provider's advice regarding treatment options and lifestyle changes.
  • Regular follow-up tests may be needed to monitor your fibrinogen levels if they were abnormal, or if you have a condition that affects fibrinogen.
  • Stay hydrated after the test. Hydration helps your veins recover after a blood draw.
  • Rest if you feel dizzy or lightheaded after the test.

Why Book with Bajaj Finserv Health?

  • Precision: Bajaj Finserv Health-recognized labs are equipped with advanced technologies ensuring the highest degree of accuracy in your test results.
  • Cost-effectiveness: We offer individual Diagnostic tests and services that are all-inclusive and don't put a strain on your wallet.
  • At-home sample collection: We provide the convenience of having your samples collected from your home at a time suitable for you.
  • Nationwide accessibility: Regardless of your location within the country, our medical test services are available to you.
  • Convenient payments: Opt from an array of payment options, either cash or digital, as per your convenience.

Note:

This is not medical advice, and this content should only be considered for informational purposes only. Consult with your healthcare provider for individual medical guidance.

Frequently Asked Questions

What type of infection/illness can Fibrinogen Blood Test detect?

1. Clotting disorders 2. Fibrinogen deficiency 3. DIC 4. Fibrinolysis

What does a high fibrinogen level mean?

High levels of fibrinogen suggest an increased risk to form clots either in the heart or the brain. It is usually seen in pregnancy, the use of oral contraceptive pills, hormone replacement therapy, and smoking.

What is the process of the Fibrinogen Test?

Fibrinogen Test is a blood test. Blood is usually collected from the front of the elbow. A tourniquet is applied to the arm to better visualise the veins. Disinfection of the site of the collection is done with an alcohol swab. A needle will be inserted into the vein, and blood is collected in the vial. Tourniquet is released and pressure is applied to the site till the bleeding stops. A gauze pad is applied to cover the site and watched for 15 minutes for any complications. You may continue with your routine after the test. The sample is taken to the lab for testing. Results should be available within 24 hours.

What test is used to detect fibrinogen abnormalities?

There are multiple tests used to qualitatively evaluate fibrinogen abnormalities. 1. Fibrinogen Antigen Test 2. Clauss method of Immunoassay 3. Genotyping.

What is the normal range of fibrinogen blood test?

Adults: 200-400 mg/dl Newborn: 125-300 mg/dl

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