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BAJAJ FINSERV HEALTH LIMITED
Stem Cell Transplant
Find the best hospitals for Stem Cell Transplant on the Bajaj Finserv Health platform.
Minimum Cost
₹15,00,000
Average Cost
₹20,00,000
Maximum Cost
₹25,00,000
- stem cell transplant cost in India depends on factors like the city, hospital and doctor.
- You can convert your stem cell transplant cost into easy, no-cost EMIs with Bajaj Finserv Health.
Quick links
- What is Stem Cell Transplant Surgery?
- Types of Stem Cell Transplant Procedure
- When is Stem Cell Transplant Operation Required?
- How to Prepare for Stem Cell Transplant Surgery?
- What Happens Before Stem Cell Transplant Surgery?
- What Happens During Stem Cell Transplant Operation?
- Methods/Techniques Used for Performing Stem Cell Transplant Procedure
- Post Procedure details
- Risks and Complications Associated with Stem Cell Transplant Surgery
- Why Bajaj Health?
What is Stem Cell Transplant Surgery?
Stem cell transplant surgery is a medical procedure wherein stem cells are transplanted into a patient's body to replace damaged or diseased cells. Stem cells are unique cells that can differentiate into different types of cells and help repair and regenerate damaged tissues.
Types of Stem Cell Transplant Procedure
Autologous Stem Cell Transplant
This is a procedure wherein stem cells are collected from the patient's own body, processed and stored for later use. This type of transplant is useful in treating diseases such as multiple myeloma, lymphoma, and some types of leukemia. Stem cells are collected from the patient's blood or bone marrow, and then high-dose chemotherapy or radiation therapy is given for destroying the diseased cells. After chemotherapy or radiation therapy, the harvested stem cells are transplanted back into the patient's body to help regenerate the damaged tissues.
Allogeneic Stem Cell Transplant
Allogeneic stem cell transplant is a procedure where stem cells are harvested from a donor, processed, and transplanted into the patient's body. This type of transplant is used to treat diseases such as leukemia, lymphoma, and myeloma. The procedure involves finding a compatible donor whose stem cells match the patient's tissue type. Once a donor is found, stem cells are harvested from the donor's blood or bone marrow and then infused into the patient's body. Before the transplant, the patient may receive high-dose chemotherapy or alternatively, radiation therapy to destroy the diseased cells and to suppress the immune system to prevent the rejection of new stem cells.
Cord Blood Transplant
A cord blood transplant is a type of allogeneic transplant where stem cells are harvested from the umbilical cord of a newborn baby. The cord blood is collected and stored in a cord blood bank till required for a transplant. This type of transplant is useful when a compatible donor cannot be found, or when the patient needs a small number of stem cells. Cord blood cells are less likely to cause graft-versus-host disease (GVHD) than other types of stem cell transplants.
Haploidentical Stem Cell Transplant
A haploidentical stem cell transplant is a type of allogeneic transplant where stem cells are harvested from a donor who is partially matched to the patient's tissue type. This type of transplant is useful when a compatible donor cannot be found. The procedure involves finding a donor whose stem cells partially match the patient's tissue type. Before the transplant, the patient may receive high-dose chemotherapy or radiation therapy to kill the diseased cells and suppress the immune system so that the new stem cells are not rejected. The harvested stem cells are then infused into the patient's body.
Mini Transplant
A mini transplant, also known as a reduced-intensity stem cell transplant, is a kind of allogeneic transplant where the patient receives a lower dose of chemotherapy or radiation therapy before the transplant. This type of transplant is useful for older patients or those with other health issues who may not be able to tolerate high-dose chemotherapy or radiation therapy. The procedure involves finding a compatible donor whose stem cells match the patient's tissue type. The patient receives a lower dose of chemotherapy or radiation therapy before the transplant, which helps to suppress the immune system and make room for the new stem cells. The harvested stem cells are then infused into the patient's body. Stem cell transplant surgery is a complex medical procedure that can treat several diseases. The type of transplant procedure used depends on the patient's condition as well as availability of a compatible donor. Procedure success depends on many factors, including the patient's age, overall health, and the extent of the disease. With proper medical care and follow-up, many patients who undergo stem cell transplant surgery can achieve long-term remission or even a cure.
When is Stem Cell Transplant Operation Required?
Stem cell transplant surgery, also known as bone marrow transplant, is a treatment procedure for some types of cancers like leukemia, lymphoma, and multiple myeloma. It is also used to treat some non-cancerous conditions, such as sickle cell anemia and certain immune system disorders. A stem cell transplant is usually recommended when other treatments like chemotherapy and radiation therapy, have not been successful in treating the cancer or disease. It may also be recommended if the cancer or disease has returned after treatment or if there is a high risk of it returning.
How to Prepare for Stem Cell Transplant Surgery?
Preparing for stem cell transplant surgery can be a complex process for which careful planning is necessary along with coordination between the patient, the healthcare team, and the patient's family and caregivers. Here are some important steps that need to be taken:
Medical Evaluation:
The patient will undergo a complete medical evaluation to identify if they are eligible for stem cell transplant surgery. These tests may involve blood tests, imaging scans, and other diagnostic tests.
Donor Selection:
If the patient is having an allogeneic stem cell transplant, a suitable donor will need to be identified. This can be a family member or an unrelated donor who matches the patient's tissue type.
Pre-transplant Conditioning:
Before the stem cell transplant, the patient will undergo a period of pre-transplant conditioning, which may include chemotherapy and/or radiation therapy. This is done so that any remaining cancer cells are killed off and the patient's immune system is suppressed so that it does not reject the transplanted cells.
Transplant Procedure:
The stem cell transplant procedure itself may involve several steps, including the collection of stem cells from the donor, the conditioning regimen, and the infusion of the stem cells into the patient's bloodstream. The procedure may take several hours or even days to complete.
Post-transplant Care:
After the stem cell transplant, the patient is typically closely monitored for any indications of complications like an infection or graft-versus-host disease (GVHD). They will also need to take medications to help prevent these complications and to support the growth of the new cells.
What Happens Before Stem Cell Transplant Surgery?
Medical evaluation:
Before the stem cell transplant surgery, a thorough medical evaluation is done to ensure that the patient is fit enough to withstand the procedure. This evaluation will include physical exams, blood tests, and imaging tests.
Choosing a donor:
If the patient is receiving stem cells from a donor, the medical team will search for a compatible donor. This is usually done through a bone marrow registry or a family member.
Pre-transplant conditioning:
The patient will be given chemotherapy and/or radiation therapy to kill cancer cells and prepare the body for the stem cell transplant. This process is known as pre-transplant conditioning or conditioning regimen.
Central venous catheter:
A central venous catheter (CVC) will be inserted into a large vein in the patient's chest. This catheter will be used to deliver stem cells and other medications during the transplant process.
Isolation:
After the conditioning regimen, the patient will be placed in isolation to prevent infections. The medical team will take precautions to protect the patient from any potential infections.
What Happens During Stem Cell Transplant Operation?
Infusion of stem cells:
The stem cells are infused into the patient's bloodstream through the central venous catheter. The stem cells will travel to the bone marrow, where they will start producing new blood cells.
Recovery:
After the stem cell infusion, the patient will need to be in the hospital for several weeks to monitor their recovery. The medical team will keep a close watch on the patient's blood counts and immune system function.
Side effects:
The patient may experience side effects during the recovery period, such as nausea, vomiting, diarrhea, fatigue, and infections. These adverse effects can be dealt with using medications and supportive care.
Graft-versus-host disease:
In some cases, the donor's immune cells may recognize the patient's body as foreign and attack it. This is known as graft-versus-host disease (GVHD). GVHD can be mild or severe; it can affect many organs in the body.
Long-term follow-up:
After the stem cell transplant, the patient will require long-term follow-up to monitor for any potential complications and to ensure the success of the transplant. The medical team may perform regular blood tests and imaging tests to monitor the patient's health. Stem cell transplant surgery is a complex and intensive procedure that requires careful planning and preparation. However, it can be a life-saving treatment for many patients with blood cancers and other serious illnesses. If you or a loved one are facing a stem cell transplant, you must discuss the potential risks and advantages with your medical team and prepare for the recovery period.
Methods/Techniques Used for Performing Stem Cell Transplant Procedure
Autologous Stem Cell Transplant:
Here, stem cells are taken from the patient's own bone marrow or blood before undergoing high-dose chemotherapy or radiation. These cells are then frozen and stored until the patient is ready for transplant. Autologous stem cell transplant is typically used to treat lymphoma, multiple myeloma, and certain types of leukemia.
Allogeneic Stem Cell Transplant:
Allogeneic stem cell transplant involves collecting stem cells from a donor, typically a family member or unrelated donor who is a close match. This procedure is often used to treat leukemia, lymphoma, and other blood disorders. Before transplant, the patient undergoes high-dose chemotherapy or radiation to destroy their existing bone marrow and immune system. The new stem cells are infused in the patient's bloodstream from where they travel to the bone marrow; they then start making new blood cells.
Umbilical Cord Blood Transplant:
This involves collecting stem cells from the placenta as well as the umbilical cord of a newborn baby. These cells are frozen and stored until needed for transplant. This type of transplant is typically used for patients who cannot find a suitable donor or who require a smaller number of stem cells.
Post Procedure details
After a stem cell transplant, patients typically stay in the hospital for several weeks to monitor their progress and manage any adverse effects. Patients may feel a range of side effects, including:Fatigue
Nausea and vomiting
Diarrhea
Infections
Low blood cell counts
Graft-versus-host disease (in allogeneic transplant) Patients will require ongoing follow-up care after leaving the hospital, including regular blood tests and check-ups with their healthcare team. It may take several months or even years for patients to fully recover from a stem cell transplant.
Risks and Complications Associated with Stem Cell Transplant Surgery
While stem cell transplants can be a life-saving treatment for many patients, it does carry risks and potential complications. The most common risks and complications of stem cell transplant include:Infection:
Patients may be at a higher infection risk due to a weakened immune system.
Graft-versus-host disease (GVHD):
In allogeneic transplant, the donor's immune cells may attack the patient's tissues and organs.
Organ damage:
High-dose chemotherapy and radiation can damage the liver, lungs, heart, and other organs.
Bleeding:
Patients may experience bleeding due to low platelet counts.
Infertility:
High-dose chemotherapy and radiation can damage the reproductive organs, leading to infertility. Patients should discuss the possible risks and complications of stem cell transplant with their healthcare team before undergoing the procedure.
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DisclaimerThe cost of stem cell transplant depends on the following factors: the city, the hospital that is selected, the complexity of the procedure and the room chosen by the patient. The price range mentioned here is an approximation of the surgery cost; Bajaj Finserv Health does not claim that these prices are an exact estimate. For exact information about surgery charges, it is best inquire at the selected hospital.